not in good physical or mental health; "ill from the monotony of his suffering"
4
unhappy
experiencing or marked by or causing sadness or sorrow or discontent; "unhappy over her departure"; "unhappy with her raise"; "after the argument they lapsed into an unhappy silence"; "had an unhappy time at school"; "the unhappy (or sad) news"; "he looks
2
insane
afflicted with or characteristic of mental derangement; "was declared insane"; "insane laughter"
