not in good physical or mental health; "ill from the monotony of his suffering"
42
miserable
very unhappy; full of misery; "he felt depressed and miserable"; "a message of hope for suffering humanity"; "wretched prisoners huddled in stinking cages"
5
unhappy
experiencing or marked by or causing sadness or sorrow or discontent; "unhappy over her departure"; "unhappy with her raise"; "after the argument they lapsed into an unhappy silence"; "had an unhappy time at school"; "the unhappy (or sad) news"; "he looks
2
brainsick
affected with madness or insanity; "a man who had gone mad"
2
suffering
troubled by pain or loss; "suffering refugees"
2
desirous
having or expressing desire for something; "desirous of high office"; "desirous of finding a quick solution to the problem"